Revlimid (lenalidomide)


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    Revlimid (lenalidomide)


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    Buy Revlimid® (lenalidomide) Online EU

    Revlimid® (lenalidomide), an immunomodulatory drug (IMiD®), is the first oral medication that was developed for treatment of multiple myeloma. It is indicated for the treatment of adult patients with multiple myeloma in combination with dexamethasone, or as maintenance following autologous hematopoietic stem cell transplantation (ASCT).

    How Does Revlimid® (lenalidomide) Work?

    Revlimid is an IMiD® compound that has immunomodulatory (affects the functioning of the immune system), tumoricidal (destroys tumor cells), and antiangiogenic (affects the blood vessels needed by tumors to grow) properties. It enhances the activity of immune cells—specialized white blood cells known as T cells and natural killer (NK) cells. Revlimid also:

    • Helps immune system recognize and destroy myeloma cells.
    • Targets and kills myeloma cells.
    • Helps prevent new myeloma cell growth by starving myeloma cells of blood.

    How Is Revlimid Given?

    Revlimid is given as a once daily capsule that is swallowed with water.

    When Revlimid is prescribed with dexamethasone, the suggested dosing is based on a 28-day dosing cycle:

    • Revlimid 25 mg every day for 21 days
    • Dexamethasone 40 mg on days 1, 8, 15, and 22
    • No Revlimid or dexamethasone on days 23-28

    When Revlimid is used as maintenance therapy after ASCT, the dosing is also based on a 28-day dosing cycle:

    • Revlimid 10 mg every day for 28 days
    • After three cycles of therapy, the dose can be increased to 15 mg once daily based on your doctor’s recommendation and how you tolerate the medication.

    Patients with kidney disease may take Revlimid, but the dosage must be adjusted according to the level of remaining kidney function, which is ascertained by a patient’s creatinine clearance value.

    Revlimid (lenalidomide) Side Effects:

    Common side effects include fatigue, diarrhea, constipation, muscle and back pain, fever, swelling, insomnia and neuropathy (nerve damage). It can cause depletion of red blood cells (anemia), white blood cells (neutropenia) and platelets (thrombocytopenia), which can lead to infections and easy bleeding.

    Potential serious side effects include deep vein thrombosis (blood clots), pulmonary embolism, heart attack, stroke, liver problems, severe skin reactions and tumor lysis syndrome (metabolic abnormalities that can occur when many cancer cells are killed at once). Like thalidomide, Revlimid can cause severe birth defects and should not be used by pregnant women or those who could become pregnant.

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